Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | hsa-miR-424 | Hepatocyte | Down | E2F Signaling pathway | Over-expression of miR-424 inhibits hepatocellular carcinoma cell proliferation by targeting AKT3. | Yang et al., 2015 |
Hepatocellular carcinoma | hsa-miR-29b | LX-1, HSC-T6 | Down | PI3K-Akt signaling pathway | hsa-miR-29b directly targets PIK3R1 and AKT3, causing inactivation of PI3K-Akt signaling pathway and inducting apoptosis of hepatic stellate cells (HSCs). | Wang et al., 2015 |