Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-544a | Stomach | Up | Wnt signaling pathway | Over-expression of miR-544a suppresses the expression of AXIN2. MicroRNA-544a promotes epithelial-mesenchymal transition via the activation of WNT signaling pathway in gastric cancer. | Yanaka et al., 2015 |
Non-small cell lung cancer | hsa-miR-582 | Lung | Up | Wnt signaling pathway | Upregulation of miR-582 down-regulates the expression of AXIN2, the negative regulators of the Wnt signaling pathway. | Fang et al., 2015 |
Ovarian cancer | hsa-miR-1207 | A2780, SK-OV-3, COV362 | Up | Wnt signaling pathway | MicroRNA-1207 plays an important role in regulating the cancer stem cell-like phenotype through targeting AXIN2 by activating the Wnt signaling pathway in ovarian cancer. | Wu et al., 2015 |