Disease Name:

Anaplastic Large Cell Lymphoma

microRNA Score: 0.0129

Gene Score: 0.0091

Pathway Score: 0.0246

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-135b Karpas-299, SU-DHL-1, SUP-M2 Up FOXO1 Jak-STAT signaling pathway hsa-miR-135b downregulates FOXO1 in anaplastic large cell lymphoma pathogenesis. miR-135b acts as a downstream mediator of Jak-STAT signaling pathway.
Matsuyama et al., 2011
hsa-miR-135b Karpas-299, SU-DHL-1, SUP-M2 Up GATA3 Jak-STAT signaling pathway hsa-miR-135b downregulates GATA3, rendering the IL-17 producing immunophenotype to anaplastic large cell lymphoma. miR-135b acts as a downstream mediator of Jak-STAT signaling pathway.
Matsuyama et al., 2011
hsa-miR-135b Karpas-299, SU-DHL-1, SUP-M2 Up STAT6 Jak-STAT signaling pathway hsa-miR-135b downregulates STAT6, rendering the IL-17 producing immunophenotype to anaplastic large cell lymphoma. miR-135b acts as a downstream mediator of Jak-STAT signaling pathway.
Matsuyama et al., 2011