| Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| hsa-miR-9 | THP-1 | JAK1 | Jak-STAT signaling pathway | MiR-9 inhibits activation of the NLRP3 inflammasome and attenuates atherosclerosis-related inflammation, through the JAK/STAT signaling pathway. | Wang et al., 2017 | |
| hsa-miR-9 | THP-1 | MMP13 | Jak-STAT signaling pathway | MiR-9 inhibits activation of the NLRP3 inflammasome and attenuates atherosclerosis-related inflammation, through the JAK/STAT signaling pathway. | Wang et al., 2017 | |
| hsa-miR-497 | HUVEC | Up | BCL2 | Caspase 3 pathway | MiR-497 plays an important role in the development of atherosclerosis by inducing apoptosis via caspase3 pathway. | Wu et al., 2016 |
| hsa-miR-497 | HUVEC | Up | CCND2 | Caspase 3 pathway | MiR-497 significantly inhibits cell proliferation by arresting the cell cycle through the CCND2 protein and induces apoptosis through the caspase3 pathway. | Wu et al., 2016 |
| hsa-miR-221 | HUVEC | PTEN | PTEN pathway | MiR-221 from human aortic smooth muscle cell-derived exosomes inhibits autophagy in HUVECs by modulating PTEN signaling pathway. | Li et al., 2016 | |
| hsa-miR-222 | HUVEC | PTEN | PTEN pathway | MiR-221 from human aortic smooth muscle cell-derived exosomes inhibits autophagy in HUVECs by modulating PTEN signaling pathway. | Li et al.,2016 | |
| hsa-miR-21 | Peripheral blood mononuclear cells | Up | TGFBR | TGF-beta signaling pathway | Overexpression of miR-21 downregulates the frequency of circulating Treg cells through TGF-beta signaling pathway in atherosclerosis. | Li et al., 2015 |
| hsa-miR-21 | Peripheral blood mononuclear cells | Up | SMAD7 | TGF-beta signaling pathway | Overexpression of miR-21 downregulates the frequency of circulating Treg cells through TGF-beta signaling pathway in atherosclerosis. | Li et al., 2015 |