Targeted Gene Name:

BCL 2

microRNA Score: 0.0172

Pathway Score: 0.0328

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Pathway More Details References
Cervical cancer hsa-miR-744 HeLa, C-4-1, Ca Ski, SiHa Up Apoptosis pathway MicroRNA-744 suppresses the expression of Bcl-2, which leads to the inactivation of apoptosis signaling and the cell proliferation of cervical cancer cells, ameliorating cervical cancer growth and progression.
Chen et al., 2016
Non-small cell lung cancer hsa-miR-16 Lung Down Caspase 3 pathway Overexpression of miR-16 enhances paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2.
Chatterjee et al., 2015
Colorectal cancer hsa-miR-375 HCT 116 BCL-2 pathway MicroRNA-375 acts as a key player in regulating the pathways responsible for inhibiting the natural history of colorectal cancer tumor cells, through the Bcl-2 pathway.
Zaharie et al., 2015
Psoriasis hsa-miR-155 HaCat Up PTEN pathway Hsa-miR-155 promotes cell proliferation and inhibits apoptosis by PTEN signaling pathway through targeting BCL 2 in the psoriasis.
Xu et al., 2017