Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Cervical cancer | hsa-miR-744 | HeLa, C-4-1, Ca Ski, SiHa | Up | Apoptosis pathway | MicroRNA-744 suppresses the expression of Bcl-2, which leads to the inactivation of apoptosis signaling and the cell proliferation of cervical cancer cells, ameliorating cervical cancer growth and progression. | Chen et al., 2016 |
Non-small cell lung cancer | hsa-miR-16 | Lung | Down | Caspase 3 pathway | Overexpression of miR-16 enhances paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2. | Chatterjee et al., 2015 |
Colorectal cancer | hsa-miR-375 | HCT 116 | BCL-2 pathway | MicroRNA-375 acts as a key player in regulating the pathways responsible for inhibiting the natural history of colorectal cancer tumor cells, through the Bcl-2 pathway. | Zaharie et al., 2015 | |
Psoriasis | hsa-miR-155 | HaCat | Up | PTEN pathway | Hsa-miR-155 promotes cell proliferation and inhibits apoptosis by PTEN signaling pathway through targeting BCL 2 in the psoriasis. | Xu et al., 2017 |