| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Non-Hodgkin lymphoma | hsa-miR-181a | SU-DHL-4, SU-DHL-10 | Up | Apoptosis pathway | Ectopic suppression of miR-181a inhibits cell adhesion dependent Bim down-regulation, resulting in cell apoptosis. hsa-miR-181a plays a significant role in the regulation of lymphoma survival and cell adhesion regulated drug resistance. | Lwin et al., 2010 |
| Mantle cell lymphoma | hsa-miR-17-92 cluster | Z-138, Granta-519, JeKo-1 | Up | PI3K-Akt signaling pathway | Overexpression of miR-17-92 cluster activates the PI3K-Akt signaling pathway through targeting BIM and inhibites chemotherapy-induced apoptosis in mantle cell lymphoma. | Rao et al., 2012 |
| Breast cancer | hsa-miR-181b | Breast | Up | miR-181b/Bim pathway | MicroRNA-181b induces chemoresistance by regulating the expression of Bim in breast cancer. | Zheng et al., 2016 |