Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-421 | MGC-803, HGC-27, BGC-823, SGC-7901 | Up | Apoptosis pathway | MicroRNA-421 functions as a tumor promoter by down-regulating the caspase-3 and inhibiting apoptosis of gastric cancer cells via repression of caspase-3 expression. | Wu et al., 2014 |
Non-small cell lung cancer | hsa-miR-224 | Lung | Up | NF-Kappa B signaling pathway | MicroRNA-224 plays an important role in the lung cancer pathogenesis through down-regulating the expression of CASP3. | Cui et al., 2015 |