Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-27b | Stomach | CREB signaling pathway | Upregulation of CREB1 is associated with lymph node metastasis, distant metastasis and tumor stage and poor outcome in gastric cancer. Over-expression of miR-27b inhibits the expression of CREB1. | Wang et al., 2015 | |
Gastric cancer | hsa-miR-200b | Stomach | CREB signaling pathway | Upregulation of CREB1 is associated with lymph node metastasis, distant metastasis and tumor stage and poor outcome in gastric cancer. MicroRNA-200b directly targets and inhibits the expression of CREB1. | Wang et al., 2015 | |
Bladder cancer | hsa-miR-433 | UM-UC-3, T24, 5637 | Down | PI3K-Akt signaling pathway | MicroRNA-433 suppresses the epithelial-mesenchymal transition in bladder cancer by targeting CREB1 through controlling PI3K-Akt signaling pathway. | Xu et al., 2016 |