Targeted Gene Name:

CYLD

microRNA Score: 0.0172

Pathway Score: 0.0328

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Pathway More Details References
T-cell acute lymphoblastic leukemia hsa-miR-19 Jurkat, MOLT-4 Up NF-Kappa B signaling pathway hsa-miR-19 regulates the expression of CYLD and controls NF-Kappa B expression in downstream signaling pathway in T-cell acute lymphoblastic leukemia.
Ye et al., 2012
Gastric cancer hsa-miR-20a Gastric cancer tissue Up NF-Kappa B signaling pathway MicroRNA-20a directly suppresses the expression of CYLD, leads to activation of the NF-Kappa B signaling pathway and the downstream targets, livin and survivin, which potentially induces gastric cancer chemoresistance.
Zhu et al., 2016
Breast cancer hsa-miR-362 Breast Up NF-Kappa B signaling pathway MicroRNA-362 regulates breast cancer cell proliferation, migration and invasion through NF-Kappa B signaling pathway.
Ni et al., 2016
Hepatocellular carcinoma hsa-miR-362 Hepatocyte Up NF-Kappa B signaling pathway hsa-miR-362 acts through CYLD to activate the NF-Kappa B signaling pathway, which promotes hepatocellular carcinoma cell growth and metastasis.
Ni et al., 2015