Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-199a | GC9811, GC9811-P, MKN28, GES-1 | Up | E CADHERIN | Suppression of miR-199a impairs the metastatic potential of gastric cancer cells. Upregulation of miR-199a-5p inhibits the expression of E-cadherin. | Zhao et al., 2014 |
Lung cancer | hsa-miR-200c | A-549 | Down | Upregulation of miR-200c suppresses cell migration and invasion with reducing the expression of EZH2 and enhancing the expression of E-cad. | Shan et al., 2016 | |
Triple negative breast cancer | hsa-miR-200a | MDA-MB-231 | EPHA2 | MicroRNA-200a suppresses migration of triple-negative breast cancer cells via direct inhibition of the EPHA2 oncogene. | Tsouko et al., 2015 |