Disease Name:

Cutaneous T-Cell Lymphoma

microRNA Score: 0.0086

Gene Score: 0.0061

Pathway Score: 0.0164

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-200c HuT 78, MyLa Down JAGGED1 Notch signaling pathway Overexpression of miR-200c suppresses the expression of Jagged1, associated with reduction of Notch1 levels in cutaneous T-cell lymphomas.
Gallardo et al., 2015
hsa-miR-122 MyLa, Se-Ax Up PI3K-Akt signaling pathway Overexpression of hsa-miR-122 decreases the sensitivity to the chemotherapy-induced apoptosis via a signaling circuit involving the activation of Akt and inhibition of p53.
Manfe et al., 2012