| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Breast cancer | hsa-miR-497 | HUVEC | PI3K-Akt signaling pathway | MicroRNA-497 suppresses tumor angiogenesis and growth through down-regulating VEGFR2 expression in breast cancer. | Tu et al., 2015 | |
| Hepatocellular carcinoma | hsa-miR-302b | Hepatocyte | Down | EGFR signaling pathway | MicroRNA-302b targets EGFR, and the cell cycle progression is arrested at the G0/G1-phase. At the same time, the expression of AKT2 is down-regulated, and CCND1 and CDK2 are reduced by miR-302b. Thus, overexpression of miR-302b inhibits the growth of hepatoma cells may due to targeting the EGFR/AKT2/CCND1 pathway. | Wang et al., 2014 |
| Prostate cancer | hsa-miR-135a-1 | PC-3, DU145 | Down | EGFR signaling pathway | Hsa-miR-135a-1 suppresses cell growth and migration of prostate cancer by down-regulating EGFR expression. | Xu et al., 2016 |
| Ovarian cancer | hsa-miR-133b | SK-OV-3, OVCAR3, HO-8910 | Up | PI3K-Akt signaling pathway | Upregulation of miR-133b suppresses proliferation and invasion of ovarian cancer cells through inhibition PI3K-Akt signaling pathways by down-regulating EGFR expression. | Liu et al., 2015 |
| Ovarian cancer | hsa-miR-7 | Ovary | Down | PI3K-Akt signaling pathway | MicroRNA-7 suppresses tumor metastasis via PI3K-Akt signaling pathway inactivation by inhibiting EGFR expression in epithelial ovarian cancer. | Zhou et al., 2014 |
| Ovarian cancer | hsa-miR-7 | Ovary | Down | ERK pathway | MicroRNA-7 suppresses tumor metastasis via ERK1/2 pathway inactivation by inhibiting EGFR expression in epithelial ovarian cancer. | Zhou et al., 2014 |