Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Acute lymphoblastic leukemia | hsa-miR-9 | TOM-1, NALM-20, Loucy, MY, Tanoue, Jurkat | Down | FGFR1 | FGFR1 is the direct targets of miR-9 and the epigenetic silencing of the tumour-suppressor gene miR-9 promotes cell proliferation by the activation of the FGFR1 oncogenic pathway in acute lymphoblastic leukemia. | Rodriguez-Otero et al., 2011 |
Schizophrenia | hsa-miR-382 | Olfactory epithelium | Up | FGFR1 | Overexpression of miR-382 downregulates FGFR1 protein level which is involved in fibroblast growth factor signaling pathway. | Mor et al., 2013 |
Schizophrenia | hsa-miR-382 | Olfactory epithelium | Up | SPRY4 | Overexpression of miR-382 downregulates SPRY4 protein level which is involved in fibroblast growth factor signaling pathway. | Mor et al., 2013 |