Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Diffuse Large B-cell lymphoma | hsa-miR-21 | OCI-Ly1, OCI-Ly18, SU-DHL-7 | Up | FOXO1 | miR-21 plays an important oncogenic role by down regulating the expression of FOXO1 and modulating the FOXO1 pathway in Diffuse Large B-cell lymphoma. | Go et al., 2015 |
Alzheimer's disease | hsa-miR-132 | Cerebral cortex | Down | FOXO3A | MicroRNA-132 regulates cell survival by direct suppression of FOXO3a, which is the key elements of AKT signaling pathway. | Wong et al., 2013 |
Alzheimer's disease | hsa-miR-212 | Cerebral cortex | Down | FOXO3A | MicroRNA-212 regulates cell survival by direct suppression of FOXO3a, which is the key elements of AKT signaling pathway. | Wong et al., 2013 |
Nasopharyngeal carcinoma | hsa-miR-421 | CNE-2 | Up | FOXO4 | MicroRNA-421 enhances nasopharyngeal carcinoma cell proliferation and anti-apoptosis by down-regulating FOXO4 expression in nasopharyngeal carcinoma. | Chen et al., 2013 |