Pathway Name:

FoxO signaling pathway

microRNA Score: 0.0172

Gene Score: 0.0122

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Diffuse Large B-cell lymphoma hsa-miR-21 OCI-Ly1, OCI-Ly18, SU-DHL-7 Up FOXO1 miR-21 plays an important oncogenic role by down regulating the expression of FOXO1 and modulating the FOXO1 pathway in Diffuse Large B-cell lymphoma.
Go et al., 2015
Alzheimer's disease hsa-miR-132 Cerebral cortex Down FOXO3A MicroRNA-132 regulates cell survival by direct suppression of FOXO3a, which is the key elements of AKT signaling pathway.
Wong et al., 2013
Alzheimer's disease hsa-miR-212 Cerebral cortex Down FOXO3A MicroRNA-212 regulates cell survival by direct suppression of FOXO3a, which is the key elements of AKT signaling pathway.
Wong et al., 2013
Nasopharyngeal carcinoma hsa-miR-421 CNE-2 Up FOXO4 MicroRNA-421 enhances nasopharyngeal carcinoma cell proliferation and anti-apoptosis by down-regulating FOXO4 expression in nasopharyngeal carcinoma.
Chen et al., 2013