Pathway Name:

GPCR pathway

microRNA Score: 0.0086

Gene Score: 0.0061

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Gastric cancer hsa-miR-146a SNU-638 Up COPS8 Upregulation of miR-146a down-regulates expression of COPS8, inhibiting GPCR-mediated activation of NF-kappaB, thus decreasing expression of NF-kappa B-regulated tumor-promoting cytokines and growth factors.
Crone et al., 2012
Gastric cancer hsa-miR-146a SNU-638 Up CARD10 Upregulation of miR-146a down-regulates expression of CARD10, inhibiting GPCR-mediated activation of NF-kappaB, thus decreasing expression of NF-kappa B-regulated tumor-promoting cytokines and growth factors.
Crone et al., 2012