Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-146a | SNU-638 | Up | COPS8 | Upregulation of miR-146a down-regulates expression of COPS8, inhibiting GPCR-mediated activation of NF-kappaB, thus decreasing expression of NF-kappa B-regulated tumor-promoting cytokines and growth factors. | Crone et al., 2012 |
Gastric cancer | hsa-miR-146a | SNU-638 | Up | CARD10 | Upregulation of miR-146a down-regulates expression of CARD10, inhibiting GPCR-mediated activation of NF-kappaB, thus decreasing expression of NF-kappa B-regulated tumor-promoting cytokines and growth factors. | Crone et al., 2012 |