Pathway Name:

Glycolysis pathway

microRNA Score: 0.0172

Gene Score: 0.0122

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Parkinson's disease hsa-miR-7 SH-SY5Y Up REL A MicroRNA-7 increases Glut3 expression, promotes glycolysis, and subsequently inhibits MPP(+)-induced cell death by targeting RelA.
Chaudhuri et al., 2015
Hepatocellular carcinoma hsa-miR-34a Hep-G2, Huh-7 Down LDHA In hepatocellular cancer cells, upregulation of miR-34a suppresses the expression of lactate dehydrogenase A (LDHA), which is a key enzyme in the glycolysis signaling pathway.
Li et al., 2016
Hepatocellular carcinoma hsa-miR-122 PLC/PRF/5 - PDK4 miR-122 inhibits hepatocellular cancer stem cells phenotypes by regulating glycolysis via down-reguating PDK4.
Song et al., 2015
Ovarian cancer hsa-miR-203 IOSE-80, IOSE-144, OVCA429, OVCA433 Up PDHB MicroRNA-203 functions as an ocogene in ovarian cancer by inducing glycolysis.
Xiaohong et al., 2016