| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | hsa-miR-18a | MGC-803, HGC-27 | Down | Apoptosis pathway | MicroRNA-18a induces gastric cancer cell apoptosis through the HIF-1-alpha/mitochondrial apoptosis pathway. | Wu et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-338 | Hepatocyte | Down | HIF signaling pathway | hsa-miR-338 suppresses HCC tumor growth and sensitizes hepatocellular carcinoma cells to sorafenib by targeting HIF-1 alpha. | Xu et al., 2014 |
| Osteosarcoma | hsa-miR-20b | MG-63, U2OS | Down | VEGF signaling pathway | MicroRNA-20b inhibits cell invasion and proliferation by down-regulating the expression of HIF-1-alpha. | Liu et al., 2016 |