Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-10b | MKN-45,GES-1 | Up | PI3K-Akt signaling pathway | MicroRNA-10b promotes the phosphorylation of RhoC and AKT through down-regulating HOXD10, thus enhancing cell invasion in gastric tumors. | Liu et al., 2012 |
Breast cancer | hsa-miR-10b | Breast | Up | ROCK pathway | MicroRNA-10b affects cytoskeletal dynamics via the ROCK pathway through targeting HOXD10. | Knirsh et al., 2016 |
Hepatocellular carcinoma | hsa-miR-10b | Hepatocyte | Up | RhoC pathway | hsa-miR-10b acts as tumor metastatic factorin hepatocellular carcinoma cell through the HOXD10/ RhoC/ uPAR/ MMPs pathway. | Liao et al., 2014 |