Pathway Name:

IFN signaling pathway

microRNA Score: 0.0172

Gene Score: 0.0122

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Hepatitis C virus infection hsa-miR-373 Hepatocyte Up JAK1 Upregulation of microRNA-373 impairs IFN signaling by down-regulating JAK1 molecules.
Mukherjee et al., 2015
Hepatitis C virus infection hsa-miR-373 Hepatocyte Up IRF9 Upregulation of microRNA-373 impairs IFN signaling by down-regulating IRF9 molecules.
Mukherjee et al., 2015
Hepatitis C virus infection hsa-miR-21 HEK293 Up MYD88 MicroRNA-21 is over-expressed during HCV infection and down-regulates IFN signaling pathway via targeting MyD88.
Chen et al., 2014
Hepatitis C virus infection hsa-miR-21 HEK293 Up IRAK1 MicroRNA-21 is over-expressed during HCV infection and down-regulates IFN signaling pathway via targeting IRAK1.
Chen et al., 2014