| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Non-small cell lung cancer | hsa-miR-223 | PC-9 | IGF 1R | MicroRNA-223 increases the acquired resistance of non-small cell lung cancer cells to erlotinib through inhibition of the IGF-1R/Akt/S6 signaling pathway. | Zhao et al., 2016 | |
| Non-small cell lung cancer | hsa-miR-99a | Lung | Down | IGF 1R | MicroRNA-99a promotes proliferation, colony formation and migration through the IGF-1R pathway in non-small cell lung cancer. | Chen et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-216b | Hepatocyte | Down | IGF2BP2 | Overexpression of hsa-miR-216b suppresses HCC cell proliferation and invasion by targeting IGF2BP2 through HBx-miR-216b-IGF2BP2 signaling pathway. | Liu et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-96 | Hepatocyte | Up | IGF 1R | Overexpression of hsa-miR-96 shows a significant downregulation of IGF-1R of oncogenic IGF signaling pathway in hepatocellular carcinoma. | Assal et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-182 | Hepatocyte | Up | IGF 1R | Overexpression of hsa-miR-182 shows a significant downregulation of IGF-1R of oncogenic IGF signaling pathway in hepatocellular carcinoma. | Assal et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-96 | Hepatocyte | Up | IGFBP 3 | Overexpression of hsa-miR-96 shows a significant downregulation of IGFBP-3 of oncogenic IGF signaling pathway in hepatocellular carcinoma. | Assal et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-182 | Hepatocyte | Up | IGFBP 3 | Overexpression of hsa-miR-182 shows a significant downregulation of IGFBP-3 of oncogenic IGF signaling pathway in hepatocellular carcinoma. | Assal et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-96 | Hepatocyte | Up | IGF-II | Overexpression of hsa-miR-96 shows a significant downregulation of IGF-II of oncogenic IGF signaling pathway in hepatocellular carcinoma. | Assal et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-182 | Hepatocyte | Up | IGF-II | Overexpression of hsa-miR-182 shows a significant downregulation of IGF-II of oncogenic IGF signaling pathway in hepatocellular carcinoma. | Assal et al., 2015 |