Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | hsa-miR-3127 | Hepatocyte | Up | PI3K-Akt signaling pathway | INPP5J is the direct target of hsa-miR-3127. hsa-miR-3127 inhibits HCC cell proliferation and tumor growth by suppressing the PI3K-Akt signaling pathway. | Jiang et al., 2015 |
Ovarian cancer | hsa-miR-661 | A2780, SK-OV-3, OVCAR | Up | PI3K-Akt signaling pathway | MicroRNA-661 functions as tumor promoter in ovarian cancer cells by down-regulates INPP5J expession. | Zhu et al., 2015 |