Pathway Name:

IRS1 signaling pathway

microRNA Score: 0.0129

Gene Score: 0.0091

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Gastric cancer hsa-miR-1271 Stomach Down IGF1R MicrRNA-1271 regulates cisplatin resistance in human gastric cancer cells through inhibiting the IGF1R/IRS1 pathway.
Yang et al., 2014
Gastric cancer hsa-miR-1271 Stomach Down IRS1 Upregulation of miR-1271 suppresses the levels of IRS1, inhibits proliferation of cells, and sensitized cells to DDP-induced apoptosis.
Yang et al., 2014
Prostate cancer hsa-miR-200c DU145, PC-3 Down IRS1 MicroRNA-200c inhibits prostate cancer cell growth by suppressing IRS1 expression.
Su et al., 2015