Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
hsa-miR-136 | A-549 | Up | IL 6 | RIG-I-dependent signaling pathway | Exogenous upregulation of microRNA-136 is associated with RIG-I-dependent signaling pathway. | Zhao et al., 2015 |
hsa-miR-24 | A-549 | Down | FURIN | Secretory pathway | hsa-miR-24 inhibits secretory pathway and modulates highly pathogenic avian-origin H5N1 influenza A virus infection. | Loveday et al., 2015 |
hsa-miR-4276 | Primary human bronchial epithelial cells | Down | COX6C | Apoptosis pathway | COX6C is an apoptotic protein that when suppressed by over-expression of miRNA-4276, allows the influenza virus to replicate and spread to neighboring healthy cells. | Othumpangat et al., 2014 |
hsa-miR-29 | A-549 | Up | DNMT | Protein kinase A signaling pathway | MicroRNA miR29 inhibits DNMT activity and regulates expression of COX2 and PGE2. Protein kinase A signaling pathway activation and CREB1 phosphorylation also associated to expression of COX2. | Fang et al., 2012 |