Targeted Gene Name:

JAGGED1

microRNA Score: 0.0129

Pathway Score: 0.0246

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Pathway More Details References
Cutaneous T-cell lymphoma hsa-miR-200c HuT 78, MyLa Down Notch signaling pathway Overexpression of miR-200c suppresses the expression of Jagged1, associated with reduction of Notch1 levels in cutaneous T-cell lymphomas.
Gallardo et al., 2015
Osteosarcoma hsa-miR-26a Zos Down Notch signaling pathway Upregulation of miR-26a inhibits the expression of Jagged1, one of the Notch ligand. MicroRNA-26a functions as tumor suppressor via suppression of Jagged1/Notch signaling.
Lu et al., 2016
Osteosarcoma hsa-miR-26a Bone Down Notch signaling pathway MicroRNA-26a suppresses stem cell-like phenotype and tumor growth of osteosarcoma by down-regulating Jagged1 expression.
Lu et al., 2016