Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Cutaneous T-cell lymphoma | hsa-miR-200c | HuT 78, MyLa | Down | Notch signaling pathway | Overexpression of miR-200c suppresses the expression of Jagged1, associated with reduction of Notch1 levels in cutaneous T-cell lymphomas. | Gallardo et al., 2015 |
Osteosarcoma | hsa-miR-26a | Zos | Down | Notch signaling pathway | Upregulation of miR-26a inhibits the expression of Jagged1, one of the Notch ligand. MicroRNA-26a functions as tumor suppressor via suppression of Jagged1/Notch signaling. | Lu et al., 2016 |
Osteosarcoma | hsa-miR-26a | Bone | Down | Notch signaling pathway | MicroRNA-26a suppresses stem cell-like phenotype and tumor growth of osteosarcoma by down-regulating Jagged1 expression. | Lu et al., 2016 |