Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Alzheimer's disease | hsa-miR-146a | SH-SY5Y | Up | PI3K-Akt signaling pathway | Upregulation of miRNA-146a significantly suppresses Lrp2 ( Low-density lipoprotein receptor-related protein-2) expression, resulting in a reduction of Akt activation and induction of proapoptotic caspase-3, thereby enhancing cell apoptosis. | Zhang et al., 2016 |