| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Non-alcoholic fatty liver disease | hsa-miR-34a | L-02 | Up | SIRT1 | Overexpression of miR-34a suppresses the expression of SIRT1. Down-regulation of miR-34a is associated with altered lipid metabolism in non-alcoholic fatty liver disease. | Ding et al., 2015 |
| Non-alcoholic fatty liver disease | hsa-miR-34a | L-02 | Up | PPARA | Overexpression of miR-34a suppresses the expression of PPAR-alpha. Down-regulation of miR-34a is associated with altered lipid metabolism in non-alcoholic fatty liver disease. | Ding et al., 2015 |
| Non-alcoholic fatty liver disease | hsa-miR-34a | Hepatocyte | Up | HNF4 ALPHA | MicroRNA-34a suppresses very low-density lipoprotein secretion and induces liver steatosis and hypolipidemia through the miR-34a-HNF4-alpha pathway. | Xu et al., 2015 |