Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-206 | Stomach | Down | c-MET signaling pathway | MicroRNA-206 acts as a tumor suppressor and inhibits the expression of c-Met in gastric cancer. | Zheng et al., 2015 |
Gastric cancer | hsa-miR-1 | AGS, SGC-7901 | Down | c-MET signaling pathway | Upregulation of miR-1 in gastric cancer cells inhibits gastric cancer cell proliferation and migration by targeting MET. | Han et al., 2015 |
Gastric cancer | hsa-miR-34a | Stomach | Down | PI3K-Akt signaling pathway | MicroRNA-34a suppresses gastric cancer tumourigenesis by down-regulating the expression of MET via the PI3K (phosphoinositide 3-kinase)/PI3K-Akt signaling pathway. | Peng et al., 2014 |
Lung cancer | hsa-miR-206 | A-549 | Down | PI3K-Akt signaling pathway | Upregulation of miR-206 decreases cisplatin resistance and epithelial-mesenchymal transition through inactivation of MET/PI3K-Akt signaling pathway. | Chen et al., 2016 |
Lung cancer | hsa-miR-31 | A-549 | Up | PI3K-Akt signaling pathway | MicroRNA-31 suppresses the growth of lung adenocarcinoma cancer stem-like cells through inhibition of the MET-PI3K-Akt signaling pathway. | Hou et al., 2016 |
Nasopharyngeal carcinoma | hsa-miR-34c | CNE-1, CNE-2, HNE-1, HONE-1 | Down | c-MET signaling pathway | hsa-miR-34c inhibits tumor growth and metastasis in nasopharyngeal carcinoma by suppressing MET. | Li et al., 2015 |
Breast cancer | hsa-miR-335 | MCF-7 | Down | c-MET signaling pathway | MicroRNA-335 inhibits breast cancer cell migration by down-regulating the HGF/c-Met pathway. | Gao et al., 2015 |
Bladder cancer | hsa-miR-433 | UM-UC-3, T24, 5637 | Down | PI3K-Akt signaling pathway | MicroRNA-433 suppresses the epithelial-mesenchymal transition in bladder cancer by targeting c-Met through controlling PI3K-Akt signaling pathway. | Xu et al., 2016 |