Disease Name:

Mantle Cell Lymphoma

microRNA Score: 0.0129

Gene Score: 0.0091

Pathway Score: 0.0246

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-17-92 cluster Z-138, Granta-519, JeKo-1 Up PHLPP2 PI3K-Akt signaling pathway Overexpression of miR-17-92 cluster activates the PI3K-Akt signaling pathway through targeting PHLPP2 and inhibites chemotherapy-induced apoptosis in mantle cell lymphoma.
Rao et al., 2012
hsa-miR-17-92 cluster Z-138, Granta-519, JeKo-1 Up PTEN PI3K-Akt signaling pathway Overexpression of miR-17-92 cluster activates the PI3K-Akt signaling pathway through targeting PTEN and inhibites chemotherapy-induced apoptosis in mantle cell lymphoma.
Rao et al., 2012
hsa-miR-17-92 cluster Z-138, Granta-519, JeKo-1 Up BIM PI3K-Akt signaling pathway Overexpression of miR-17-92 cluster activates the PI3K-Akt signaling pathway through targeting BIM and inhibites chemotherapy-induced apoptosis in mantle cell lymphoma.
Rao et al., 2012