| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Hepatitis C virus infection | hsa-miR-449a | Hep-G2 | Down | Notch signaling pathway | MicroRNA-449a plays an important role in regulating the expression of YKL40 through down-regulating NOTCH1 which is the components of the NOTCH signaling pathway. | Sarma et al., 2012 |
| Gastric signet ring cell carcinoma | hsa-miR-935 | GES-1, AGS, MKN28, MKN45, KATO III, SGC-7901 | Down | Notch signaling pathway | MicroRNA-935 suppresses gastric carcinoma cell proliferation, migration and invasion by directly inhibiting the expression of Notch1. | Yan et al., 2016 |
| Triple negative breast cancer | hsa-miR-9 | MDA-MB-231 | Up | Notch signaling pathway | MicroRNA-9 elicits a suppressor-like activity in metastatic breast cancer cells by targeting Notch1. | Mohammadi-Yeganeh et al., 2015 |
| Breast cancer | hsa-miR-34a | MCF-7 | Down | Notch signaling pathway | MicroRNA-34a suppresses breast cancer stemness and enhances the chemosensitivity to paclitaxel by targeting the Notch1 pathway. | Kang et al., 2015 |
| Cervical cancer | hsa-miR-34a | HeLa, Ca Ski, SiHa | Down | Notch signaling pathway | MicroRNA-34a suppresses invasiveness in cervical cancer through targeting the Notch pathway. | Pang et al., 2010 |
| Choriocarcinoma | hsa-miR-34a | BeWo, JAR | Down | Notch signaling pathway | MicroRNA-34a suppresses invasiveness in choriocarcinoma through targeting the Notch pathway. | Pang et al., 2010 |