Disease Name:

Nasopharyngeal carcinoma

microRNA Score: 0.0733

Gene Score: 0.0518

Pathway Score: 0.1393

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-34c CNE-1, CNE-2, HNE-1, HONE-1 Down MET c-MET signaling pathway hsa-miR-34c inhibits tumor growth and metastasis in nasopharyngeal carcinoma by suppressing MET.
 Li et al., 2015
hsa-miR-92a CNE-1, CNE-2 Up PTEN PI3K-Akt signaling pathway MicroRNA-92a induces metastasis of nasopharyngeal carcinoma by down-regulating the PI3K-Akt signaling pathway.
 Zhang et al., 2016
hsa-miR-133b CNE-2, HONE1 Down S1PR1 Jak-STAT signaling pathway MicroRNA-133b inhibits proliferation of nasopharyngeal carcinoma cell by down-regulating S1PR1 expression.
 Cheng et al., 2016
hsa-miR-141 HNE-1 Up PTEN PI3K-Akt signaling pathway MicroRNA-141 promotes cell proliferation and tumor formation in nasopharyngeal carcinoma through targeting PI3K-Akt signaling pathway.
 Liu et al., 2016
hsa-miR-24 CNE-1, CNE-2 Down SP1 miR-24/SP1 pathway MicroRNA-24 increases radiosensitivity by down-regulating SP1 expression in nasopharyngeal carcinoma.
 Kang et al., 2016
hsa-miR-200a CNE-2 Up NF-Kappa B signaling pathway MicroRNA-200a promotes nasopharyngeal carcinoma cell proliferation through activating the NF-Kappa B signaling pathway.
 Shi et al., 2016
hsa-miR-4792 CNE-2, HONE1 Down FOXC1 miR-4792/FOXC1 pathway MicroRNA-4792 acts as a tumor suppressor in development and progression of nasopharyngeal carcinoma by down-regulating FOXC1 expression.
 Li et al., 2015
hsa-miR-539 Nasopharynx Down CDK4 CDK pathway MicroRNA-539 promotes the progression of nasopharyngeal carcinoma by down-regulating CDK4 expression.
 Lv et al., 2015
hsa-miR-23a CNE-1, CNE-2 Down IL 8 Jak-STAT signaling pathway Decreased expression of miR-23a enhances nasopharyngeal carcinoma cell radioresistance through activation of Jak-STAT signaling pathway.
 Qu et al., 2015
hsa-miR-93 CNE-1, CNE-2, HONE1 Up DAB2 miR-93/Dab2 pathway MicroRNA-93 enhances cell growth and invasion in nasopharyngeal carcinoma by down-regulating Dab2 expression.
 Xu et al., 2015
hsa-miR-101 CNE-2 Down STMN1 miR-101/STMN1 pathway MicroRNA-101 regulates cell viability, radioresistance and radiation-induced autophagy by down-regulating stathmin 1 expression in nasopharyngeal carcinoma.
 Sun et al., 2015
hsa-miR-185 CNE-2 Down WNT2B Wnt signaling pathway MicroRNA-185 controls the radioresistance of nasopharyngeal carcinoma through targeting WNT2B expression.
 Li et al., 2014
hsa-miR-93 CNE-1, CNE-2 Down TGFBR2 PI3K-Akt signaling pathway MicroRNA-93 enhances uncontrolled growth, invasion, metastasis of nasopharyngeal carcinoma through activating PI3K-Akt signaling pathway by inhibiting TGF-beta-R2 expression.
 Lyu et al., 2014
hsa-miR-9 NP69 Down CXCR4 p38 MAPK signaling pathway MicroRNA-9 acts as a tumor-suppressive microRNA by down-regulating CXCR4 expression in nasopharyngeal carcinoma.
 Lu et al., 2014
hsa-miR-451 NP69 Down MIF MIF signaling pathway Over-expression of miR-451 inhibits cell viability, colony formation, and cell migration and invasion by targeting MIF.
 Liu et al., 2013
hsa-miR-421 CNE-2 Up FOXO4 FoxO signaling pathway MicroRNA-421 enhances nasopharyngeal carcinoma cell proliferation and anti-apoptosis by down-regulating FOXO4 expression in nasopharyngeal carcinoma.
 Chen et al., 2013
hsa-miR-324 CNE-2 Down WNT2B Wnt signaling pathway MicroRNA-324 controls the radioresistance of nasopharyngeal carcinoma by inhibiting the Wnt signaling pathway.
 Li et al., 2013


© Regenerative Medicine Lab, 2024.

School of Medical Science and Technology, IIT Kharagpur .

mirWay Team: Sankha Subhra Das, Pritam Saha and Nishant Chakravorty.

Indian Institute of Technology Kharagpur.

Last updated: April 04, 2024