Disease Name:

Non-Hodgkin Lymphoma

microRNA Score: 0.0043

Gene Score: 0.003

Pathway Score: 0.0082

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-28 Germinal Center B cells Down BAG1 ERK pathway hsa-miR-28 targets BCL2-associated athanogene (BAG1) involved in proliferation and apoptosis. BAG1 is an activator of the ERK pathway.
Schneider et al., 2014
hsa-miR-181a SU-DHL-4, SU-DHL-10 Up BIM Apoptosis pathway Ectopic suppression of miR-181a inhibits cell adhesion dependent Bim down-regulation, resulting in cell apoptosis. hsa-miR-181a plays a significant role in the regulation of lymphoma survival and cell adhesion regulated drug resistance.
Lwin et al., 2010