Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
hsa-miR-28 | Germinal Center B cells | Down | BAG1 | ERK pathway | hsa-miR-28 targets BCL2-associated athanogene (BAG1) involved in proliferation and apoptosis. BAG1 is an activator of the ERK pathway. | Schneider et al., 2014 |
hsa-miR-181a | SU-DHL-4, SU-DHL-10 | Up | BIM | Apoptosis pathway | Ectopic suppression of miR-181a inhibits cell adhesion dependent Bim down-regulation, resulting in cell apoptosis. hsa-miR-181a plays a significant role in the regulation of lymphoma survival and cell adhesion regulated drug resistance. | Lwin et al., 2010 |