Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Diffuse Large B-cell lymphoma | hsa-miR-124 | OCI-Ly1, OCI-Ly18, SU-DHL-7 | Up | PI3K-Akt signaling pathway | MicroRNA-124 controls glucocorticoid sensitivity by down regulating phosphodiesterase 4B (PDE4B). This is associated with increased cAMP levels, suppression of the PI3K-Akt signaling pathway in diffuse large B cell lymphoma. | Kim et al., 2015 |
Diffuse Large B-cell lymphoma | hsa-miR-124 | OCI-Ly1, OCI-Ly18, SU-DHL-7 | Up | mTOR pathway | MicroRNA-124 controls glucocorticoid sensitivity by down regulating phosphodiesterase 4B (PDE4B). This is associated with increased cAMP levels, suppression of the mTOR pathway in diffuse large B cell lymphoma. | Kim et al., 2015 |
Diffuse Large B-cell lymphoma | hsa-miR-124 | OCI-Ly1, OCI-Ly18, SU-DHL-7 | Up | MCL1 pathway | MicroRNA-124 controls glucocorticoid sensitivity by down regulating phosphodiesterase 4B (PDE4B). This is associated with increased cAMP levels, suppression of the MCL1 pathway in diffuse large B cell lymphoma. | Kim et al., 2015 |