Targeted Gene Name:

PDE4B

microRNA Score: 0.0129

Pathway Score: 0.0246

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Pathway More Details References
Diffuse Large B-cell lymphoma hsa-miR-124 OCI-Ly1, OCI-Ly18, SU-DHL-7 Up PI3K-Akt signaling pathway MicroRNA-124 controls glucocorticoid sensitivity by down regulating phosphodiesterase 4B (PDE4B). This is associated with increased cAMP levels, suppression of the PI3K-Akt signaling pathway in diffuse large B cell lymphoma.
Kim et al., 2015
Diffuse Large B-cell lymphoma hsa-miR-124 OCI-Ly1, OCI-Ly18, SU-DHL-7 Up mTOR pathway MicroRNA-124 controls glucocorticoid sensitivity by down regulating phosphodiesterase 4B (PDE4B). This is associated with increased cAMP levels, suppression of the mTOR pathway in diffuse large B cell lymphoma.
Kim et al., 2015
Diffuse Large B-cell lymphoma hsa-miR-124 OCI-Ly1, OCI-Ly18, SU-DHL-7 Up MCL1 pathway MicroRNA-124 controls glucocorticoid sensitivity by down regulating phosphodiesterase 4B (PDE4B). This is associated with increased cAMP levels, suppression of the MCL1 pathway in diffuse large B cell lymphoma.
Kim et al., 2015