Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-34a | Stomach | Down | PI3K-Akt signaling pathway | MicroRNA-34a suppresses gastric cancer tumourigenesis by down-regulating PDGFR via the PI3K (phosphoinositide 3-kinase)/PI3K-Akt signaling pathway. | Peng et al., 2014 |
Ovarian cancer | hsa-miR-140 | A2780, SK-OV-3, OVCAR | Down | miR-140-5p-PDGFRA pathway | Upregulation of miR-140 significantly suppresses ovarian cancer cell proliferation and promotes apoptosis by targeting PDGFRA. | Lan et al., 2015 |