Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | hsa-miR-126 | A-549 | Down | PI3K-Akt signaling pathway | Over-expression of miR-126 decreases the expression of the target gene PIK3R2 and regulates the PI3K-Akt signaling pathway, inhibiting the proliferation, migration, and invasion of non-small-cell lung cancer. | Song et al., 2016 |
Bladder cancer | hsa-miR-126 | BLS-1 | Up | PI3K-Akt signaling pathway | Upregulation of miR-126 inhibits proliferation, migration, and invasion and enhances apoptosis by down-regulating PIK3R2 expression through regulating PI3K-Akt signaling pathway in bladder cancer. | Xiao et al., 2016 |