| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Non-alcoholic fatty liver disease | hsa-miR-34a | L-02 | Up | Lipid metabolism pathway | Overexpression of miR-34a suppresses the expression of PPAR-alpha. Down-regulation of miR-34a is associated with altered lipid metabolism in non-alcoholic fatty liver disease. | Ding et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-9 | Hepatocyte | Up | PPAR signaling pathway | hsa-miR-9 controls CDH1 expression through directly targeting CDH1 and indirectly through PPARA. hsa-miR -9 is the key regulator of HCC oncogenesis via PPAR signaling pathway. | Drakaki et al., 2015 |