| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Acute myeloid leukemia | hsa-miR-181a | KG-1a, MV4-11, HL-60, HEK293T | Up | KRAS | hsa-miR-181a targets RAS signaling pathway through downregulating KRAS and decreases acute myeloid leukemia growth. | Huang et al., 2016 |
| Acute myeloid leukemia | hsa-miR-181a | KG-1a, MV4-11, HL-60, HEK293T | Up | NRAS | hsa-miR-181a targets RAS signaling pathway through downregulating NRAS and decreases acute myeloid leukemia growth. | Huang et al., 2016 |
| Acute myeloid leukemia | hsa-miR-181a | KG-1a, MV4-11, HL-60, HEK293T | Up | MAPK1 | hsa-miR-181a targets RAS signaling pathway through downregulating MAPK1 and decreases acute myeloid leukemia growth. | Huang et al., 2016 |
| Hepatitis C virus infection | hsa-miR-199a | Huh-7.5.1 | Up | MicroRNA-199a promotes HCV replication by regulating Ras/ERK pathway. | Wang et al., 2015 | |
| Gastric cancer | hsa-miR-27a | MGC-803, AGS, BGC-823, HGC-27, SGC-7901 | Up | BTG2 | Upregulation of miR-27a increases gastric cancer cell proliferation through targeting BTG2. | Zhou et al., 2016 |
| Colorectal cancer | hsa-miR-622 | Colorectum | Down | K RAS | MicroRNA-622 suppresses colorectal cancer occurrence and metastasis by down-regulating the expression of K-Ras. | Fang et al., 2016 |
| Ovarian cancer | hsa-miR-634 | A2780 | Down | ERK2 | MicroRNA-634 regains drug sensitivity in resistant ovarian cancer cells by down-regulating the RAS signaling pathway. | Jaarsveld et al., 2015 |