Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | hsa-miR-200b | BEL-7402, SMMC-7221 | Down | RhoA pathway | Over-expression of miR-200b significantly inhibits lung metastasis in hepatocellular carcinoma cells through targeting ROCK2. | Wong et al., 2015 |
Hepatocellular carcinoma | hsa-miR-200b | Hepatocyte | Down | RhoA pathway | ROCK2 is the downstream target of hsa-miR-200b. Re-expression of hsa-miR-200b suppresses lung metastasis through downregulating RhoA pathway. | Wong et al., 2015 |