| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Pancreatic carcinoma | hsa-miR-940 | SW1990 | Up | Wnt signaling pathway | Over-expression of miR-940 significantly represses sFRP1 expression and enhances pancreatic carcinoma proliferation and invasion. | Yang et al., 2016 |
| Non-small cell lung cancer | hsa-miR-582 | Lung | Up | Wnt signaling pathway | Increased expression of miR-582 inhibits the expression of SFRP1, the negative regulators of the Wnt signaling pathway. | Fang et al., 2015 |
| Ovarian cancer | hsa-miR-1207 | A2780, SK-OV-3, COV362 | Up | Wnt signaling pathway | MicroRNA-1207 plays an important role in regulating the cancer stem cell-like phenotype through targeting SFRP1 by activating the Wnt signaling pathway in ovarian cancer. | Wu et al., 2015 |
| Pancreatic carcinoma | hsa-miR-744 | PANC-1, BxPC-3, CFPAC-1, Capan-1 | Up | Wnt signaling pathway | MicroRNA-744 promotes tumorigenicity in pancreatic cancer by directly targeting secreted frizzled-related protein 1 (SFRP1), important negative regulator of Wnt signaling pathway. | Zhou et al., 2015 |