| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | hsa-miR-543 | BGC-823, AGS, GES-1 | Up | SIRT1 | MicroRNA-543 induces gastric cancer cell proliferation by down-regulating the expression of SIRT1. | Li et al., 2016 |
| Gastric cancer | hsa-miR-204 | Stomach | Down | SIRT1 | Down-regulation of miR-204 is associated with gastric cancer cell invasion via regulation of the SIRT1-LKB1 pathway. | Zhang et al., 2013 |
| Chronic pancreatitis | hsa-miR-217 | PANC-1, BxPC-3 | Down | SIRT1 | Expression of miR-217 is significantly decreased in chronic pancreatitis cell and its expression is negatively correlated with SIRT1 expression. | Deng et al., 2014 |