| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Pulmonary arterial hypertension | hsa-miR-126 | Right ventricular | Down | VEGF signaling pathway | Decreased expression of miR-126 is associated with increased Sprouty-related EVH1 domain-containing protein 1 (SPRED-1) expression, leading to decreased activation of RAF and MAPK, thus inhibiting the vascular endothelial growth factor pathway. | Potus et al., 2015 |
| Myocarditis | hsa-miR-126 | HeLa | Up | ERK pathway | MicroRNA-126 activates ERK pathway through targeting SPRED1 and enhances CVB3 replication. | Ye et al., 2013 |