| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Hepatitis C virus infection | hsa-miR-185 | Hep-G2 | SREBP2 | Upregulation of microRNA-185 suppresses the expression of SREBP2 by HCV core protein. | Li et al., 2015 | |
| Hepatitis C virus infection | hsa-miR-122 | Hep-G2 | HCBP6 | Over-expression of microRNA-122 suppresses the expression of HCBP6 (hepatitis C virus core-binding protein 6) which modulates TG (Triglyceride) Homeostasis in Hepatocytes through the SREBP pathway. | Gao et al., 2015 | |
| Hepatocellular carcinoma | hsa-miR-449 | Hepatocyte | SIRT1 | MicroRNA-449 inhibits SIRT1-SREBP signaling via downregulating expression of SIRT1 and re-programs lipogenesis and cholesterogenesis in hepatocellular carcinoma. | Zhang et al., 2014 |