Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-874 | Stomach | Down | Jak-STAT signaling pathway | Down-regulation of miR-874 is associated with tumor angiogenesis through STAT3 in gastric cancer. | Zhang et al., 2015 |
Gastric cancer | hsa-miR-106b | AGS, MKN45 | Down | Jak-STAT signaling pathway | Over-expression of miR-106b suppresses the expression of STAT3. Gastric epithelial cells treated with H. pylori LPS may be susceptible to activation of JAK/STAT3 signal pathway. | Ye et al., 2015 |
Pancreatic carcinoma | hsa-miR-1181 | PANC-1, BxPC-3, CFPAC-1, Capan-1, Capan-2 | Down | Jak-STAT signaling pathway | MicroRNA-1181 downregulates STAT3 expression, resulting in inhibition of the Jak-STAT signaling pathway in pancreatic cancer. | Jiang et al., 2015 |