Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
hsa-miR-106b | HuT 78, H9, HH | Up | PTEN | PI3K-Akt signaling pathway | Overexpression of hsa-miR-106b downregulates the expression of PTEN. Reduced PTEN activates the PI3/AKT-mediated pathway of cell growth and survival. | Cristofoletti et al., 2013 |
hsa-miR-21 | HuT 78, H9, HH | Up | PTEN | PI3K-Akt signaling pathway | Overexpression of hsa-miR-21 downregulates the expression of PTEN. Reduced PTEN activates the PI3/AKT-mediated pathway of cell growth and survival. | Cristofoletti et al., 2013 |
hsa-miR-486 | HuT 78, H9, HH | Up | PTEN | PI3K-Akt signaling pathway | Overexpression of hsa-miR-486 downregulates the expression of PTEN. Reduced PTEN activates the PI3/AKT-mediated pathway of cell growth and survival. | Cristofoletti et al., 2013 |