Disease Name:

Sezary Syndrome

microRNA Score: 0.0129

Gene Score: 0.0091

Pathway Score: 0.0246

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-106b HuT 78, H9, HH Up PTEN PI3K-Akt signaling pathway Overexpression of hsa-miR-106b downregulates the expression of PTEN. Reduced PTEN activates the PI3/AKT-mediated pathway of cell growth and survival.
Cristofoletti et al., 2013
hsa-miR-21 HuT 78, H9, HH Up PTEN PI3K-Akt signaling pathway Overexpression of hsa-miR-21 downregulates the expression of PTEN. Reduced PTEN activates the PI3/AKT-mediated pathway of cell growth and survival.
Cristofoletti et al., 2013
hsa-miR-486 HuT 78, H9, HH Up PTEN PI3K-Akt signaling pathway Overexpression of hsa-miR-486 downregulates the expression of PTEN. Reduced PTEN activates the PI3/AKT-mediated pathway of cell growth and survival.
Cristofoletti et al., 2013