Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-130 | Gastric cancer tissue | Up | TGF-beta signaling pathway | MicroRNA-130 acts as an oncogene and promotes cell proliferation by directly inhibiting the expression of TGF-beta-R2 in gastric cancer. | Duan et al., 2016 |
Nasopharyngeal carcinoma | hsa-miR-93 | CNE-1, CNE-2 | Down | PI3K-Akt signaling pathway | MicroRNA-93 enhances uncontrolled growth, invasion, metastasis of nasopharyngeal carcinoma through activating PI3K-Akt signaling pathway by inhibiting TGF-beta-R2 expression. | Lyu et al., 2014 |
Asthma | hsa-miR-19a | Bronchial epithelial cell | Up | TGF-beta signaling pathway | hsa-miR-19a increased bronchial epithelial cell proliferation in severe asthma through inhibiting TGF-beta receptor 2 mRNA level. | Haj-salem et al., 2015 |