Pathway Name:

Toll-like receptor signaling pathway

microRNA Score: 0.0172

Gene Score: 0.0122

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Chronic lymphocytic leukemia hsa-miR-17-92 cluster Peripheral blood Up miR-17-92 family regulates pro-survival and growth-promoting responses of chronic lymphocytic leukemia cells to TLR9 triggering.
Bomben et al., 2012
Hepatitis C virus infection hsa-miR-146a Peripheral blood monocyte Up MicroRNA-146a expression is abnormally enhanced in peripheral blood monocytes of HCV-infected patients. The Toll-like receptor signaling pathway takes part in the upregulation of miR-146a in monocytes stimulated with HCV core protein.
Zhang et al., 2015
Hepatitis C virus infection hsa-miR-146a Peripheral blood mononuclear cells Down HCV infection suppresses the induction of miR-146a by modulating Toll-like receptor signaling pathway.
El-Ekiaby et al., 2012
Hepatitis C virus infection hsa-miR-155 Peripheral blood mononuclear cells Down HCV infection suppresses the induction of miR-155 by modulating Toll-like receptor signaling pathway.
El-Ekiaby et al., 2012