Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Chronic lymphocytic leukemia | hsa-miR-17-92 cluster | Peripheral blood | Up | miR-17-92 family regulates pro-survival and growth-promoting responses of chronic lymphocytic leukemia cells to TLR9 triggering. | Bomben et al., 2012 | |
Hepatitis C virus infection | hsa-miR-146a | Peripheral blood monocyte | Up | MicroRNA-146a expression is abnormally enhanced in peripheral blood monocytes of HCV-infected patients. The Toll-like receptor signaling pathway takes part in the upregulation of miR-146a in monocytes stimulated with HCV core protein. | Zhang et al., 2015 | |
Hepatitis C virus infection | hsa-miR-146a | Peripheral blood mononuclear cells | Down | HCV infection suppresses the induction of miR-146a by modulating Toll-like receptor signaling pathway. | El-Ekiaby et al., 2012 | |
Hepatitis C virus infection | hsa-miR-155 | Peripheral blood mononuclear cells | Down | HCV infection suppresses the induction of miR-155 by modulating Toll-like receptor signaling pathway. | El-Ekiaby et al., 2012 |