| Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| hsa-miR-223 | MCF-7, MDA-MB-231, MDA-MB-435, SK-BR-3 | Down | HAX1 | Mitochondria/ROS pathway | MicroRNA-223 enhances the sensitivity of triple-negative breast cancer to TRAIL-induced apoptosis by down-regulating the expression of HAX-1. | Sun et al., 2016 |
| hsa-miR-498 | MCF-7, MDA-MB-231, SK-BR-3 | Up | BRCA1 | BRCA1 pathway | Upregulation of miR-498 regulates the pathogenesis of sporadic triple negative breast cancer through BRCA1 downregulation. | Matamala et al., 2016 |
| hsa-miR-7 | MDA-MB-231 | RAF 1 | Raf signaling pathway | Decreased expression of miR-7 by lapatinib is associated with the activation of Raf-1 signaling pathway in triple-negative breast cancer. | Hsiao et al., 2015 | |
| hsa-miR-200a | MDA-MB-231 | EPHA2 | Cadherin signaling pathway | MicroRNA-200a suppresses migration of triple-negative breast cancer cells via direct inhibition of the EPHA2 oncogene. | Tsouko et al., 2015 | |
| hsa-miR-200b | MCF-7, MDA-MB-231, MDA-MB-157 | RhoGDI pathway | MicroRNA-200b inhibits the RhoGDI pathway, which leads to non-canonical suppression of epithelial-to-mesenchymal transition in triple-negative breast cancer. | Rhodes et al., 2015 | ||
| hsa-miR-200b | MCF-7, MDA-MB-231, MDA-MB-157 | RhoGDI pathway | MicroRNA-200b inhibits the RhoGDI pathway, which leads to non-canonical suppression of epithelial-to-mesenchymal transition in triple-negative breast cancer. | Rhodes et al., 2015 | ||
| hsa-miR-9 | MDA-MB-231 | Up | NOTCH1 | Notch signaling pathway | MicroRNA-9 elicits a suppressor-like activity in metastatic breast cancer cells by targeting Notch1. | Mohammadi-Yeganeh et al., 2015 |