Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | Hepatocyte | Down | IRS1 | PI3K-Akt signaling pathway | Upregulation of miR-105 reduces hepatocellular carcinoma proliferation by downregulating the expression of IRS1 of PI3K-Akt signaling pathway. | Shen et al., 2014 |
Hepatocellular carcinoma | Hepatocyte | Down | AKT | PI3K-Akt signaling pathway | Upregulation of miR-105 reduces hepatocellular carcinoma proliferation by downregulating the expression of AKT1 of PI3K-Akt signaling pathway. | Shen et al., 2014 |
Hepatocellular carcinoma | Hepatocyte | Down | PDK1 | PI3K-Akt signaling pathway | Upregulation of miR-105 reduces hepatocellular carcinoma proliferation by downregulating the expression of PDK1 of PI3K-Akt signaling pathway. | Shen et al., 2014 |