| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Hepatitis C virus infection | Hep-G2 | Down | JAK1 | IL-6-mediated signaling pathway | MicroRNA-107 regulates IL-6-mediated CCL2 expression and STAT3 phosphorylation by down-regulating JAK1. | Sarma et al., 2014 |
| Non-small cell lung cancer | Lung | Down | BDNF | PI3K-Akt signaling pathway | MicroRNA-107 inhibits non-small cell lung cancer metastasis by down-regulating brain-derived neurotrophic factor and indirectly regulating PI3K-Akt signaling pathway. | Xia et al., 2016 |
| Cervical cancer | HeLa, SiHa | Down | MCL1 | ATR/Chk1 pathway | MicroRNA-107 inhibits cervical cancer invasion through activating ATR/Chk1 pathway. | Zhou et al., 2014 |