Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | Lung | Up | PTEN | PI3K-Akt signaling pathway | Upregulation of miR-10a enhances non-small cell lung cancer cell proliferation, migration and invasion through targeting PTEN. | Yu et al., 2015 |
Lung cancer | A-549 | Up | TGF-beta signaling pathway | MicroRNA-10a is the potential target for improving the effectiveness of lung cancer chemotherapy through the regulation of the TGF-beta/Smad2/STAT3/STAT5 pathway. | Sun et al., 2015 | |
Asthma | Airway smooth muscle | Up | PIK3CA | PI3K-Akt signaling pathway | MicroRNA-10a regulates human airway smooth muscle cell proliferation through targeting PI3K-Akt signaling pathway. | Hu et al., 2014 |