Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Acute lymphoblastic leukemia | TOM-1, NALM-20, Loucy, MY, Tanoue, Jurkat | Down | CDK6 | CDK pathway | Down-regulation of miR-124a promotes up-regulation of its target, CDK6, and phosphorylation of retinoblastoma (Rb) and contributes to the abnormal proliferation of acute lymphoblastic leukemia cells. | Agirre et al., 2009 |